On-Farm Antimicrobial Usage in Turkey Production
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Turkey companies participated voluntarily and represented a large percentage of the overall U.S. turkey production
- The antimicrobial use datasets represent approximately 71% of turkey produced annually based on USDA:National Agricultural Statistics Service published numbers
- The antimicrobial use data that were submitted for 2023 include information on more than 173,000,000 poults placed, 151,000,000 turkeys slaughtered, and more than 4,880,000,000 pounds liveweight produced
Key Findings
Several key diseases were targeted by antimicrobial administration
- Clostridial dermatitis, a clostridial disease of turkeys, remains one of the most important diseases of turkeys that requires antimicrobial therapy
- Bacterial enteritis also comprises a considerable fraction of the overall antimicrobial use in turkey production, typically in the young poults
- Colibacillosis, a broad category of E. coli diseases that affect turkeys, results in much of the antimicrobial use in feed and water
- Avian metapneumovirus has caused severe morbidity and mortality in turkey flocks. Infection with this virus can lead to an increased incidence of secondary bacterial infections, resulting in increased antimicrobial use, when effective
Antimicrobial use by all routes decreased substantially between 2013 and 2024
Hatchery Antimicrobials
- The approximate percentage of turkey poults placed that received hatchery antimicrobials decreased from 97% in 2013 to 45% in 2024
- Hatchery gentamicin use in turkey poults decreased almost 40% between 2013 and 2024
In-Feed Antimicrobials
- In-feed tetracycline use decreased approximately 16% between 2013 and 2024
- Some approved uses of in-feed antimicrobial drugs were discontinued with implementation of GFI #213
- There are no remaining approved uses of virginiamycin or in-feed tylosin in turkeys, and thus use of both of these antimicrobial drugs in-feed went to zero in 2017
Water-Soluble Antimicrobials
- Medically important water-soluble antibiotic use in turkeys decreased substantially 2013-2019 and then stabilized or increased slightly 2019-2024. Increases were typically due to increased disease incidence, as seen in other countries, during the 2019-2024 period
- Water-soluble penicillin use decreased by more than 49% since 2013
- Water-soluble lincomycin use decreased 58% from 2013 to 2019 but has increased almost fivefold from 2019-2024 due to increases in clostridial dermatitis incidence and a shortage of penicillin
- Water-soluble tetracycline use decreased 21% from 2013-2022 but increased approximately 54% from 2022-2024, largely due to increases in colibacillosis
- Water-soluble neomycin use decreased by more than 67% since 2013
- Medically important water-soluble antibiotic use in turkeys decreased substantially 2013-2019 and then stabilized or increased slightly 2019-2024. Increases were typically due to increased disease incidence, as seen in other countries, during the 2019-2024 period
There were substantial reductions in the use of most medically important antimicrobials in turkey production, regardless of route of administration
- While a reduction in antimicrobial use may be an important indicator of improved stewardship, reducing the need for antimicrobials through improved disease prevention should be considered a more holistic indicator of overall flock health and optimal antimicrobial use
Acknowledgments
This project is funded with multiple annual grants from the U.S. Poultry & Egg Association. The project was also partly supported from 2016 to 2023 under a cooperative agreement with the U.S. Food and Drug Administration (U01FD005878). Beginning in September 2024, a new cooperative agreement between FDA-CVM and Mindwalk Consulting Group (U01FD008419) was initiated. This ongoing monitoring program would not be possible without the voluntary participation of layer, broiler chicken and turkey companies of the U.S. as well as support from the National Chicken Council, National Turkey Federation, United Egg Producers.
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